Effect of malaria parasites’ infection on CD4 cells, haemopoietic cells and haemopoietic factors

Abstract Malariology Immunity is essential for understanding the pathology, treatment & vaccine production. Changes in CD4, haemopoietic cells factors (RBC/HB/PCV/MCV/MCH MCHC) malaria parasites-infected patients were studied at a teaching hospital Enugu, Nigeria. 45 on doctor’s provisional diagnosis of examined Plasmodiuminfections degree parasitaemia (0/+/++/& +++). Positive (+) negative (0) samples thereafter counted CD4/haemopoietic using Flow Cytometry/Automated Blood Cell Counter, respectively. Plasmodium-negative specimens within reference ranges CD4 cell count (464–1308); mean value: 835. Fifteen showed lower (502–1282); mean: 678; with immune falls one (427). Nine from twelve (++) crash counts, range: 301–415; 399. Seven (+++) crashes 160–357; 225. Significant rise increase occurs neutrophils and Total WBC. Opposite occurred three other primary platelets. There variances basic cells’ percent numeric. The haemoglobin didn’t exhibited significant change, except platelet that marked steady decrease parasitaemia. Plasmodiuminfection causes immunosuppression patients, vivid changes populations/percentages, Malaria infection immunodeficients shouldaccelerate complications, including death, unlike prevailing reports. Haemolytic anaemia likely complication resulting only chronic cases since there was no this study None